![]() ![]() Idarucizumab is a monoclonal antibody fragment binding dabigatran with neutralizing effect on anticoagulation. Despite the increasing use of direct oral anticoagulants, there currently are no available drug-specific reversal agents. N Engl J Med 2015 373:511-520.ĭabigatran is a direct thrombin inhibitor utilized for stroke prevention in patients with non-valvular atrial fibrillation (AF), and for venous thromboembolism prevention and treatment. Editor's Note: Commentary based on Pollack CV Jr, Reilly PA, Eikelboom J, et al. ![]()
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